Mouse C1 Inhibitor Genetically Deficient Spleen Lyophilized from Innovative Research is prepared from a C1 Inhibitor Homozygous Knockout Mouse. This C1 Inhibitor Homozygous Knockout was created by targeted excision of the SERPING1 gene. Homozygous mice completely lack C1 Inhibitor protein expression. Organ is flash-frozen immediately upon removal, then lyophilized.

Product Details:

• Species:Mouse
• Antigen:C1 Inhibitor
• Format:Lyophilized
• Storage Conditions:2° to 8°C

This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like hemorrhagic shock, septic shock, transplant rejection, reperfusion injury, inflammatory disorders, and hereditary angioedema.

Mouse Model Details

• Strain:C57BL6/SJL
• Chromosome:2
• Gene:SERPING1
• Genomic TargetIntron 1, Exon 8
• Mutation:9244 base pair deletion
• Phenotype:Absence of C1 Inhibitor protein expression and increased vascular permeability

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